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Compulsive drug use despite negative consequences indicating impaired control over usage. Differs from dependence.

Breakthrough Pain

Temporary flare up of moderate-severe pain in those with persistent pain controlled by medications.

Phantom Limb Pain

Perception of pain seeming to come from the part of a limb removed by amputation that makes the brain think the limb is still present.

Physical Dependence

Adaptations to the body such that stopping some medications after prolonged use (like opioids) causes withdrawal sickness from lack of drug activity.

Referred Pain

Pain perceived at a location different from the site of origin/tissue irritation due to shared nerve pathways.

Substance Use Disorder

Problematic pattern of uncontrolled use of medications or illegal drugs that causes life disruptions.

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