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Matthew P. Jaycox, MD - Pain Management in Chicago, Illinois

Nerve Blocks
Targeted nerve blocks to interrupt pain signals
Spinal Cord Stimulation
Implantable devices to manage chronic pain
Regenerative Medicine
PRP therapy and stem cell treatments
Medication Management
Prescription management and medication optimization
Injection Therapy
Corticosteroid and other therapeutic injections for pain relief
Physical Therapy
Exercises and treatments to improve mobility and reduce pain
About Matthew P. Jaycox, MD — Rush Pain Center, Chicago, IL
Matthew P. Jaycox, MD, is a board-certified pain management physician and anesthesiologist practicing at Rush Pain Center, affiliated with Rush University Medical Center in Chicago, Illinois. The clinic holds a patient rating of 4.8 out of 5 and serves people living with both acute and chronic pain conditions across multiple locations, including Chicago, Oak Park, and Westchester, IL.
Dr. Jaycox completed his medical degree, anesthesiology residency, and pain management fellowship at Rush University Medical Center. He currently serves as Associate Program Director of the Pain Management Fellowship there, practicing as both a clinician and an academic educator. The clinic also participates in NIH-funded pain research, connecting patients to care informed by ongoing scientific inquiry.
Treatment Approach
Rush Pain Center uses a multidisciplinary, biopsychosocial model of care. The physician team includes specialists in pain management and anesthesiology — among them Sandeep Amin, MD, Asokumar Buvanendran, MD, Timothy R. Lubenow, MD, Adam C. Young, MD, Tolga Suvar, MD, and William Landphair, DO — alongside Patricia A. Merriman, Ph.D., a counseling psychologist whose work focuses specifically on chronic pain.
Services that may help people manage pain include:
- Injection treatments such as epidural steroid injections, facet joint injections, medial branch blocks, and sympathetic nerve blocks
- Radiofrequency neurolysis and ablation (rhizotomy)
- Spinal cord stimulation (SCS) and dorsal root ganglion (DRG) stimulation
- Intrathecal pump implantation
- Platelet rich plasma (PRP) treatment
- Minimally invasive spine treatment, with Dr. Lubenow having authored published guidelines in this area
- Medication management with an emphasis on opioid-limiting, individualized treatment plans — Dr. Jaycox has served on the Rush University Medical Center Opiate Safety Committee
- Counseling psychology for chronic pain
- Physical therapy and diagnostic services
What Patients Can Expect
Reviewers consistently describe Dr. Jaycox as thorough and clear in explaining diagnoses and treatment options in language that is easy to understand. Patients note feeling heard during appointments, and several reviewers with clinical backgrounds — including registered nurses — express strong confidence in his level of expertise. Long-term patient retention appears across multiple reviews, with people describing years of ongoing care.
Patients also describe the broader staff, including front desk personnel, as friendly and attentive. The clinic recommends scheduling appointments in advance. The facility is fully ADA accessible, with a wheelchair-accessible entrance, parking lot, and washroom. Payment is accepted via credit card, debit card, and NFC mobile payment.
Rush Pain Center's affiliated ambulatory surgery center was ranked #1 in Chicago and #2 in Illinois in America's Best Ambulatory Surgery Centers 2023, as recognized by Newsweek.
Divya Agrawal, M.D
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Adam Delora, MD
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William Landphair, D.O
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Robin Mata, DO, MPH
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Antonio Navarro, MD
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Abdulhameed Qashqary, M.B.B.S
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Taruna Waghray-penmetcha, M.D
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Bryan Williams, MD
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Patients often mention Dr. Matthew P. Jaycox as a knowledgeable and attentive physician who takes time to explain diagnoses and treatment options in clear, approachable language. Reviewers note that his warm and occasionally humorous bedside manner helps ease anxiety, and many describe feeling genuinely heard and respected during appointments. His ability to think through challenging or complex cases draws particular praise, and patients with medical backgrounds, including nurses, express strong confidence in his clinical judgment. Reviewers also appreciate his proactive approach to identifying potential health concerns before they escalate. The front desk staff receives positive mentions as well, contributing to an overall welcoming environment. Many patients describe years of ongoing care with Dr. Jaycox, reflecting a high level of trust built over time, and a number actively refer family and friends to his practice. On the less positive side, patients note that his schedule tends to stay full, and one reviewer reported a concern about a prescription not being received following an appointment. Overall, Dr. Jaycox holds a rating of 4.8 out of 5 across more than 200 reviews.
What Patients Say
Patient Testimonials
“Dr. Jaycox is very knowledgeable and explained my injury and potential treatment indepthly but easy to understand. He took his time to answer all the questions my husband and I asked. I feel very confident with his treatment suggestion and scheduled the procedure ASAP. He has a fantastic personality, very warm and congenial and humorous. I was nervous up until the appointment and he made me feel very comfortable. Thank you!”
— Lucille
“Not sure what I would do without Dr Jaycox on my care team. His knowledge and professionalism is beyond compare especially as it pertains to supporting me with my chronic, complex conditions. He is always very busy in clinic but he always makes me feel heard and seen which I really appreciate.”
— Melissa Beilstein
“My doctor was retiring and I had to choose another doctor in the practice. I had had a couple of interactions with Dr. Jaycox over the years that I have been at the practice and instantly liked his energy and responsiveness. There was no choice for me, Dr. Jaycox is now my pain doctor and I am very pleased. As many chronic pain patients know, having a doctor that you can trust, that trusts you, and that you can communicate well with is no small thing. It's everything.”
— Nikki Koll
“Dr.Jaycox is a great doctor. He is very knowledgeable. He spends time with you and listens to what you have to say and does not just brush you off. He explains so you understand. He is very caring and has a great bedside manor. I highly recommend him if you are looking for a pain specialist, you definitely will not be disappointed.”
— Bernita Murphy
Insurance Accepted
Please verify insurance coverage and payment options directly with the clinic before your visit.
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Opens at 8:00 AM
- MondayClosed
- TuesdayClosed
- WednesdayClosed
- Thursday(Today)8:00 AM - 4:00 PM
- FridayClosed
- SaturdayClosed
- SundayClosed
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